Clinical Trials Directory

Trials / Completed

CompletedNCT00889759

The Role of High Resolution-Computed Tomography (CT) in Tuberculosis (TB) Outbreak Investigation

The Role of Addition of High Resolution-CT in Outbreak Investigation of Tuberculosis

Status
Completed
Phase
Study type
Observational
Enrollment
92 (actual)
Sponsor
Armed Forces Capital Hospital, Republic of Korea · Other Government
Sex
Male
Age
Healthy volunteers
Accepted

Summary

The aim of this study is to evaluate the role of high-resolution computed tomography of the chest (HRCT) in the investigation of an outbreak of TB that developed in the South Korean army.

Detailed description

Outbreak investigation including tuberculin skin test (TST), QuantiFERON® TB Gold In-Tube (QFT), and simple chest radiography (CXR) will be performed. For participants with any abnormal findings in these tests, HRCT will be carried out. Active pulmonary TB is diagnosed based on sputum studies or HRCT findings. In addition, participants with positive results both in TST and QTF will be treated as having a latent TB infection (LTBI). TST and QTF were repeated in participants with positive result in one of these tests. CXR will be repeated in all participants at 3 and 6 months of follow-up.

Conditions

Timeline

Start date
2007-12-01
Primary completion
2009-01-01
Completion
2009-04-01
First posted
2009-04-29
Last updated
2009-09-23

Source: ClinicalTrials.gov record NCT00889759. Inclusion in this directory is not an endorsement.