NCT00888290

Sodium Bicarbonate Supplementation in Chronic Kidney Disease Evaluation of Dose Response, Safety and Beneficial Effects

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: Albert Einstein College of Medicine · Academic / Other
• Sex: All
• Age: 21 Years
• Healthy volunteers: Not accepted

Summary

This study will enroll 25 patients with kidney disease to evaluate the effects of different doses of sodium bicarbonate (baking soda) on levels of bicarbonate in the blood, kidney function and muscle strength. The investigators will also evaluate safety and tolerability of different doses.

Detailed description

This study enrolled 20 patient to evaluate the effects of different doses of sodium bicarbonate. We will test serum bicarbonate levels, potassium levels and muscle function.

Conditions

• Chronic Kidney Disease

Interventions

Type	Name	Description
DRUG	Sodium bicarbonate	Sodium bicarbonate at 3 different doses or placebo. The different doses tested will be: 0.3 mEq/kg of ideal body weight, 0.6 mEq/kg of ideal body weight and 1 mEq/kg pf ideal body weight
DRUG	Placebos	Placebo at 3 different doses to match Sodium bicarbonate dosing

Timeline

• Start date: 2009-03-01
• Primary completion: 2010-05-01
• Completion: 2010-05-01
• First posted: 2009-04-27
• Last updated: 2022-08-30
• Results posted: 2022-08-30

Locations

1 site across 1 country: United States