NCT00887029

A 12 Week Comparison of DuoTrav and Xalacom in Open-Angle Glaucoma

A 12 Week Comparison of DuoTrav and Xalacom at 24 Hours Post-Dose in the Treatment of Open-Angle Glaucoma (the DVX Study)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: Ophthalmic Consultants Centres, Canada · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Hypothesis: * H1: Efficacy of Duotrav will be superior to Xalacom at 24 hours post dosing when both medications are given in the morning * H2: A significant proportion of patients will prefer dosing of once daily topical fixed combination therapy in the morning compared to evening dosing

Detailed description

* Primary objective: Compare IOP-lowering efficacy of morning dosing of Duotrav to Xalacom. * Secondary objective: Compare patient dosing preferences for topical prostaglandin therapy in terms of convenience and perceived compliance.

Conditions

• Open-Angle Glaucoma
• Ocular Hypertension

Interventions

Type	Name	Description
DRUG	DuoTrav (travoprost-timolol ophthalmic drops)	topical ophthalmic drops instilled 1 drop daily
DRUG	Xalacom (latanoprost-timolol ophthalmic drops)	topical ophthalmic drops instilled 1 drop daily

Timeline

• Start date: 2009-01-01
• Primary completion: 2009-11-01
• Completion: 2009-11-01
• First posted: 2009-04-23
• Last updated: 2015-04-21

Locations

2 sites across 1 country: Canada