NCT00886704

Omega-3 Fatty Acids, the Omega-3 Index, and Atherosclerosis

Influence of Dietary Omega-3 Fatty Acids in a Convenience Drink (Smartfish) on the Omega-3 Index in Patients With Atherosclerotic Disease

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: Ludwig-Maximilians - University of Munich · Academic / Other
• Sex: All
• Age: 30 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

An increase in intake of omega-3 fatty acids should increase the Omega-3 Index. Current evidence indicates that this may lead to a reduction in risk for sudden cardiac death and atherosclerotic diseases like myocardial infarction. The aim of the study is to investigate, how supplementing a convenience drink with omega-3 fatty acids influences the Omega-3 Index, as compared to an unsupplemented matching convenience drink. Palatability and safety of the drink are also to be assessed.

Conditions

• Atherosclerosis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	500 mg eicosapentaenoic (EPA) plus docosahexaenoic acids (DHA)	Composition of active convenience drink (smartfish): 200 ml drink, enriched with 940 mg omega-3 fatty acids, of which 200 mg are EPA, 300 mg DHA and 100 mg DPA, slightly carbonized.. Energy content 486 kJ (116 kcal), protein 0.6 g, Carbohydrates 22 g, total fat 4 g, of which 0.6 g saturated fatty acids, 1.8 g monounsaturates, 1.4 g polyunsaturates. Vitamin D 0.85 ug. Control convenience drink: as above, containing about 1 g Omega-6 fatty acids from e.g. corn oil.
DIETARY_SUPPLEMENT	Control convenience drink	Control convenience drink: as above, containing about 1 g Omega-6 fatty acids from e.g. corn oil.

Timeline

• Start date: 2009-04-01
• Primary completion: 2009-08-01
• Completion: 2009-09-01
• First posted: 2009-04-23
• Last updated: 2011-10-07
• Results posted: 2011-09-26

Locations

1 site across 1 country: Germany