NCT00886678

A Study of Pemetrexed Plus Carboplatin Combined With Radiation in Patients With Inoperable Locally Advanced Non-small Cell Lung Cancer (LA-NSCLC) (RT0801)

A Phase II Study of Pemetrexed Plus Carboplatin Combined With Radiation in Patients With Inoperable Locally Advanced Non-small Cell Lung Cancer

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 63 (estimated)
• Sponsor: Zhejiang Cancer Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Patients with inoperable Non-Small-Cell Lung Cancer will receive thoracic radiation therapy 66 Gy over 33 fractions,and concurrent with 2 cycles of chemotherapy with pemetrexed (500 mg/m2,d1,repeated every 3 weeks)and carboplatin (AUC=5,d1,repeated every 3 weeks).

Conditions

• Non-Small Cell Lung Cancer

Interventions

Type	Name	Description
DRUG	pemetrexed	500 mg/m2, IV, q 21 days x 2 cycles
DRUG	carboplatin	AUC=5,IV,q 21 days x 2 cycles
RADIATION	thoracic radiation	66 Gy over 33 fractions

Timeline

• Start date: 2008-07-01
• Primary completion: 2010-07-01
• Completion: 2010-07-01
• First posted: 2009-04-23
• Last updated: 2011-02-24

Locations

1 site across 1 country: China