Trials / Completed
CompletedNCT00885391
QT Variability Pre and Post Cardioversion
QT Variability Pre & Post Cardioversion in Patient's With Atrial Fibrillation
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 219 (actual)
- Sponsor
- Vanderbilt University · Academic / Other
- Sex
- All
- Age
- 21 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to learn whether the chemicals in the blood and urine are different when the heart is atrial fibrillation compared to normal sinus rhythm.
Detailed description
Atrial Fibrillation variably activates the renin-angiotensin-aldosterone system (RAAS), stimulates the sympathetic nervous system, generates oxidant stress, produces natriuretic peptides, and increases ventricular rate. These are interrelated responses and the extent to which these or other pathophysiologic responses determine QT interval during and after Atrial Fibrillation (AF) is unknown. In this study, the QT variability is related to those potential markers in patients with AF undergoing elective DC-cardioversion.
Conditions
Timeline
- Start date
- 2007-01-01
- Primary completion
- 2012-03-01
- Completion
- 2012-03-01
- First posted
- 2009-04-22
- Last updated
- 2014-12-11
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT00885391. Inclusion in this directory is not an endorsement.