NCT00882622

Effect of Remote Ischemic Preconditioning on Cardiac Function After Cardiac Surgery

• Status: Withdrawn
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Patrick Meybohm · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the effects of Remote Ischemic Preconditioning on cardiac function in patients undergoing cardiac surgery compared to control intervention.

Detailed description

In detail, we will focus on new onset of atrial fibrillation, ventricular arrhythmias, myocardial injury, and cardiac function. Furthermore, we aim to investigate underlying pathways of RIPC in modifying the perioperative stress response.

Conditions

• Atrial Fibrillation
• Ventricular Arrythmias
• Myocardial Injury
• Cardiac Function

Interventions

Type	Name	Description
PROCEDURE	Remote Ischemic Preconditioning	RIPC will be induced during anesthesia by four 5-min cycles of upper limb ischemia and 5-min reperfusion using a blood-pressure cuff inflated to a pressure 15 mm Hg greater than the systolic arterial pressure measured via the arterial line.
PROCEDURE	Control/sham procedure	Sham placement of the blood pressure cuff around the upper limb without inflation.

Timeline

• Start date: 2009-02-01
• Primary completion: 2009-02-01
• Completion: 2009-02-01
• First posted: 2009-04-16
• Last updated: 2012-01-18

Locations

2 sites across 1 country: Germany