Trials / Completed
CompletedNCT00877305
Effect of Remote Ischemic Preconditioning on Cognitive Function After Cardiac Surgery
- Status
- Completed
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 180 (actual)
- Sponsor
- Patrick Meybohm · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate the effects of Remote Ischemic Preconditioning on cognitive function in patients undergoing cardiac surgery compared to control intervention.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Remote Ischemic Preconditioning | RIPC will be induced during anesthesia by four 5-min cycles of upper limb ischemia and 5-min reperfusion using a blood-pressure cuff inflated to 200 mmHg (at least a pressure 15 mm Hg greater than the systolic arterial pressure measured via the arterial line). |
| OTHER | Control | Sham intervention with four 5-min cycles of inflation of the blood pressure cuff at 20 mmHg and 5 min deflation without any upper leg ischaemia. |
Timeline
- Start date
- 2008-10-01
- Primary completion
- 2010-11-01
- First posted
- 2009-04-07
- Last updated
- 2012-01-18
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT00877305. Inclusion in this directory is not an endorsement.