Clinical Trials Directory

Trials / Completed

CompletedNCT00876031

Trial for Localised High-risk Rhabdomyosarcoma and Rhabdomyosarcoma-like Soft Tissue Sarcoma

A Randomised Phase-III Trial of the Cooperative Weichteilsarkom Study Group (CWS) for Localised High-risk Rhabdomyosarcoma and Localised Rhabdomyosarcoma-like Soft Tissue Sarcoma in Children, Adolescents, and Young Adults

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
195 (actual)
Sponsor
University Hospital Tuebingen · Academic / Other
Sex
All
Age
6 Months – 21 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to investigate whether the addition of oral maintenance chemotherapy with O-TIE (Etoposide, Idarubicin, Trofosfamide) for 6 months improves the event free survival (EFS) in patients with localised high-risk RMS and RMS-like Soft Tissue Sarcoma.

Conditions

Interventions

TypeNameDescription
DRUGtrofosfamide, idarubicin, etoposideoral maintenance therapy for 6 months

Timeline

Start date
2009-07-01
Primary completion
2022-06-30
Completion
2022-06-30
First posted
2009-04-06
Last updated
2022-11-08

Locations

87 sites across 5 countries: Austria, Germany, Poland, Sweden, Switzerland

Source: ClinicalTrials.gov record NCT00876031. Inclusion in this directory is not an endorsement.