Clinical Trials Directory

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UnknownNCT00874146

Level of HER2-neu Gene Amplification an Response to Trastuzumab

Retrospective Study of the Level of HER2-neu Gene Amplification as Predictive Factor of Response in Patients With HER2-positive Advanced Breast Cancer Treated With Trastuzumab Containing Regimens.

Status
Unknown
Phase
Study type
Observational
Enrollment
100 (estimated)
Sponsor
Istituto Clinico Humanitas · Academic / Other
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

Primary objective of the study is to evaluate the correlation between level of HER2-neu gene amplification evalued by dual-color Fluorescent in-situ hybridization (FISH) test and time to progression (TTP) in patients with HER2-positive advanced breast cancer treated with trastuzumab-containing regimens.

Conditions

Interventions

TypeNameDescription
GENETICFluorescent in-situ hybridization (FISH)Dual color FISH test to assess ratio of HER2/neu amplification

Timeline

Start date
2009-03-01
Primary completion
2009-09-01
Completion
2009-12-01
First posted
2009-04-02
Last updated
2010-09-02

Locations

1 site across 1 country: Italy

Source: ClinicalTrials.gov record NCT00874146. Inclusion in this directory is not an endorsement.