NCT00868387

Macronutrient Relations and Weight Loss in Obese Subjects

Effects of Macronutrient Relations on Body Weight, Body Composition, and Cardiovascular Risk Markers in Overweight Patients Attending a Telemedically Guided Weight Loss Program

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (actual)
• Sponsor: Heart and Diabetes Center North-Rhine Westfalia · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The burden of overweight and obesity has dramatically increased during the last decades. High carbohydrate intake, particularly refined carbohydrates, probably increase the risk of obesity, type 2 diabetes, and metabolic syndrome. There is evidence that energy-restricted low-carbohydrate diets show greater weight loss and better improvement of cardiovascular risk markers compared to energy-restricted low-fat diets. Beside macronutrient relations, efficacy of weight loss programs depends on care and control. The investigators aim to investigate whether or not a carbohydrate-restricted telemedically guided weight loss program results in a more pronounced weight loss and influences metabolic risk markers more beneficial than a fat-restricted diet.

Detailed description

see brief summary.

Conditions

• Obesity

Interventions

Type	Name	Description
OTHER	energy-restricted, CHO-restricted diet	carbohydrate content of the diet \< 40% Frequency: daily Duration: 12 months
OTHER	energy-restricted, CHO-rich diet	carbohydrate content of diet \> 55% Frequency: daily Duration: 12 months

Timeline

• Start date: 2005-11-01
• Primary completion: 2006-11-01
• Completion: 2007-12-01
• First posted: 2009-03-25
• Last updated: 2017-03-22

Locations

1 site across 1 country: Germany