Clinical Trials Directory

Trials / Completed

CompletedNCT00868192

Trial of Pemetrexed and Bevacizumab for Recurrent Ovarian Primary Peritoneal Carcinoma

Phase II Trial of Pemetrexed and Bevacizumab for Recurrent Ovarian and Primary Peritoneal Carcinoma

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
38 (actual)
Sponsor
Washington University School of Medicine · Academic / Other
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to determine if the combination of bevacizumab and pemetrexed have an effect on recurrent ovarian and primary peritoneal carcinoma by looking at progression and survival at 6 months.

Detailed description

Patients will be treated with pemetrexed 500 mg/m2 IV and Bevacizumab 15 mg/kg IV every 3 weeks.The patient is treated indefinitely until side effects are deemed severe by the investigator or until progression. Disease progression is measured every 6 weeks using RECIST criteria.

Conditions

Interventions

TypeNameDescription
DRUGPemetrexed
DRUGBevacizumab

Timeline

Start date
2008-05-01
Primary completion
2012-12-01
Completion
2012-12-01
First posted
2009-03-24
Last updated
2014-10-20
Results posted
2014-10-20

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT00868192. Inclusion in this directory is not an endorsement.