Trials / Unknown
UnknownNCT00863967
Early Detection of Arteriosclerosis
Prospective Observational Cohort Study for Early Detection of Arteriosclerosis
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 269 (actual)
- Sponsor
- Kantonsspital Baselland Bruderholz · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Arteriosclerosis is a common chronic disease with well known risk factors like diabetes mellitus, hypertension, dyslipidemia, adipositas and smoking, leading to severe complications like myocardial infarction, stroke or peripheral arterial occlusive disease. In addition to life-style factors there is also a genetic predisposition to develop complicated atherosclerosis. Objective: Improve individual risk prediction by clinical phenotyping and genotyping.
Detailed description
About 300 patients who are treated for various conditions at the department of general medicine at our hospital will be included prospectively in the study. This observational cohort will be followed for at least 10 years follow-up examinations. At baseline and during follow up visits detailed clinical phenotyping is planned (medical and family history,standardized clinical and physical examinations, lab, RX, ECG, stress-test or echocardiogram). The genotyping is performed by DNA-isolation from leucocytes collected at baseline.
Conditions
- Arteriosclerosis
- Atherosclerosis
- Myocardial Infarction
- Stroke
- Diabetes Mellitus
- Peripheral Arterial Occlusive Disease
Timeline
- Start date
- 2003-10-01
- Primary completion
- 2015-10-01
- Completion
- 2015-10-01
- First posted
- 2009-03-18
- Last updated
- 2009-03-18
Source: ClinicalTrials.gov record NCT00863967. Inclusion in this directory is not an endorsement.