Trials / Completed
CompletedNCT00863213
Study of Ablation Versus antiaRrhythmic Drugs in Persistent Atrial Fibrillation
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 152 (actual)
- Sponsor
- Hospital Clinic of Barcelona · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to compare the effectivity and safety of atrial fibrillation ablation, in comparison to antiarrhythmic drug therapy in patients with refractory, persistent atrial fibrillation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Atrial fibrillation ablation | Atrial fibrillation ablation with radiofrequency, guided by 3D navigation map. Either 4mm or cooled tip-catheters will be used. It will include, at least, pulmonary veins isolation; all other radiofrequency lines, including roof and mitral isthmus line, and complex fractioned electrograms ablation will be performed according to each Hospital protocol. Radiofrequency lines block will be tested. |
| DRUG | Antiarrhythmic drug | Usual drug therapy for atrial fibrillation. In patients with structural heart disease, amiodarone is recommended, while flecainide plus diltiazem or beta-blockers are encouraged in patients without structural heart diseases. |
Timeline
- Start date
- 2009-03-01
- Primary completion
- 2011-03-01
- Completion
- 2012-12-01
- First posted
- 2009-03-17
- Last updated
- 2013-04-26
Locations
8 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT00863213. Inclusion in this directory is not an endorsement.