NCT00859573

Modafinil for Methamphetamine Dependence

Clinical Efficacy of Modafinil in Recently-Abstinent Methamphetamine-Dependent Volunteers

• Status: Terminated
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: University of Arkansas · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Fifty methamphetamine dependent treatment-seeking volunteers will be enrolled in this 10 week, double bind, placebo controlled, randomized clinical trial to receive either modafinil or placebo. Eligible subjects will reside at the Recovery Centers of Arkansas residential facility to achieve initial abstinence and be inducted onto study medication during wks 1-2. Then during wks 3-10, subjects participate on an outpatient basis, receiving weekly psychotherapy while continuing to receive study medications. Urine samples will be collected thrice weekly and self reports weekly to assess methamphetamine use. It is hoped that the results of this study will contribute to our understanding of which types of agents may be good candidates for further development as potential treatment agents for this disorder.

Conditions

• Methamphetamine Dependence

Interventions

Type	Name	Description
DRUG	Modafinil	400 mg/day
DRUG	Placebo	inactive substance

Timeline

• Start date: 2009-04-01
• Primary completion: 2010-01-01
• Completion: 2010-01-01
• First posted: 2009-03-11
• Last updated: 2017-11-21
• Results posted: 2011-07-15

Locations

1 site across 1 country: United States