Clinical Trials Directory

Trials / Completed

CompletedNCT00855660

Effect of Riociguat on Bone Metabolism

Investigation of the Effect of Riociguat, Administered as 2.5 mg IR-tablets TID Over 14 Days, on Bone Metabolism in a Randomized, Placebo-controlled, Double-blind, 2-fold Cross-over Design in Healthy Male Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
17 (actual)
Sponsor
Bayer · Industry
Sex
Male
Age
18 Years – 45 Years
Healthy volunteers
Accepted

Summary

Investigation of the effect of Riociguat, administered as 2.5 mg IR-tablets TID over 14 days, on bone metabolism.

Detailed description

Clinical pharmacology

Conditions

Interventions

TypeNameDescription
DRUGRiociguat (Adempas, BAY63-2521) immediate release tablet of 2.5 mgRiociguat administered in a dose of 2.5 mg (single tablet), thrice daily, over 14 days.
DRUGPlaceboPlacebo administered as a single tablet, thrice daily, over 14 days.

Timeline

Start date
2009-03-01
Primary completion
2009-12-01
Completion
2010-07-01
First posted
2009-03-04
Last updated
2016-01-11

Locations

1 site across 1 country: Germany

Source: ClinicalTrials.gov record NCT00855660. Inclusion in this directory is not an endorsement.