NCT00854724

Puerarin Effects on Alcohol Drinking

Puerarin (NPI-031G) Effects on Alcohol Drinking - A Natural Settings Study

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 16 (actual)
• Sponsor: Mclean Hospital · Academic / Other
• Sex: All
• Age: 21 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This research is designed to assess the impact of pretreatment with puerarin (NPI-031G), a major ingredient in the plant kudzu, on alcohol drinking. Hypothesis: Short-term treatment with this compound will reduce alcohol self-administration in a simulated natural settings laboratory.

Detailed description

Participants will have an opportunity to drink up to 6 beers, plus water and juice, during a 90 minute afternoon drinking session in our simulated apartment room laboratory. Drinking sessions will be conducted in the afternoon after participants take puerarin or placebo for 7 days.

Conditions

• Alcohol Abuse

Interventions

Type	Name	Description
DRUG	Puerarin, Placebo	400 mg, three times a day for 7 days

Timeline

• Start date: 2009-02-01
• Primary completion: 2011-03-01
• Completion: 2011-07-01
• First posted: 2009-03-03
• Last updated: 2011-09-09
• Results posted: 2011-08-12

Locations

1 site across 1 country: United States