NCT00851305

Detection of Early Gastric Cancers Using Confocal Laser Endomicroscopy

Comparison Confocal Laser Endomicroscopy With Conventional Endoscopy for the Detection of Early Gastric Cancers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,786 (actual)
• Sponsor: Shandong University · Academic / Other
• Sex: All
• Age: 45 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to determine whether endomicroscopy can improve the detection of Early Gastric Cancers (EGC).

Detailed description

Endoscopy is proved to be the best method to achieve early diagnosis of gastric cancer (GC). Confocal laser endomicroscopy (CLE), a new diagnostic modality, has been shown to be valuable in increasing the diagnostic yield of colorectal neoplasias, but it is not clear whether CLE is helpful to find out early gastric cancer (EGC).The aim of the study is to investigate the value of CLE in improving the detection of EGCs.

Conditions

• Stomach Neoplasms
• Precancerous Conditions

Interventions

Type	Name	Description
DEVICE	Endomicroscope (Pentax, Tokyo, Japan)	A Pentax EC3870K endomicroscope which can produce conventional white light endoscopic images and confocal images at the same time with a optical slice thickness of 7 μm, a lateral resolution of 0.7 μm, a scanning depth of 0 to 250 μm, a pixel density of 1024×512 pixels (at an image acquisition rate of 1.6 frames/second)，and a field of view of 475 μm×475 μm.
DEVICE	Gastroscopes (Pentax, Tokyo, Japan)	Conventional white light gastroscopes (Pentax EG-2940 gastroscopes)

Timeline

• Start date: 2008-08-01
• Primary completion: 2009-07-01
• Completion: 2009-07-01
• First posted: 2009-02-25
• Last updated: 2012-07-17

Locations

1 site across 1 country: China