NCT00850746

A Study to Evaluate the Effect of Repeat Oral Doses of YM443 on Cardiac Repolarization in Healthy Adults

A Phase 1, Randomized, Double-Blind, Placebo- and Active- Controlled, Crossover Study to Evaluate the Effect of Repeat Oral Doses of YM443 on Cardiac Repolarization in Healthy Male and Female Adult Subjects

• Status: Completed
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Astellas Pharma Inc · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

This study evaluates whether YM443 causes any changes in the electrocardiogram of healthy adults.

Detailed description

Each subject participates in all four treatment periods separated by washout periods. In order to maintain the blind between arms, all subjects will receive the same number of tablets per day in each period of either active drug or placebo.

Conditions

• Functional Dyspepsia

Interventions

Type	Name	Description
DRUG	YM443	Oral
DRUG	Placebo	Oral
DRUG	Moxifloxacin	Oral

Timeline

• Start date: 2009-02-01
• Primary completion: 2009-04-01
• Completion: 2009-04-01
• First posted: 2009-02-25
• Last updated: 2014-03-24

Locations

1 site across 1 country: United States