NCT00850278

Assessment of [18F]FLT-PET Imaging for Diagnosis and Prognosis of Brain Tumors

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (actual)
• Sponsor: University Hospital, Caen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this study is to assess the efficacy of the radiopharmaceutical 3'-deoxy-3'-\[F-18\]fluorothymidine, \[F-18\]FLT, a tracor of cell proliferation, using Positron Emission Tomography (PET) imaging for the tumor diagnosis and prognosis in a group of 50 patients with different type of brain tumors.\[F-18\]FLT PET imaging will be compared to the current used imaging techniques of MRI, spectroscopy imaging, PET imaging using \[11C\]MET tracer, immunohistochemical analysis and clinical parameters.

Conditions

• Cancer
• Brain Tumors

Interventions

Type	Name	Description
OTHER	FLT-PET imaging	Prior to surgical resection, patient will undergo \[11C\]MET PET imaging, \[18F\]FLT PET imaging, MRI, and spectroscopy imaging.

Timeline

• Start date: 2008-10-01
• Primary completion: 2011-07-01
• Completion: 2011-07-01
• First posted: 2009-02-24
• Last updated: 2026-04-02

Locations

1 site across 1 country: France