Clinical Trials Directory

Trials / Terminated

TerminatedNCT00850239

Safety and Efficacy Study of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Multi-Center Study to Evaluate Safety and Efficacy of Dutogliptin/PHX1149T in Subjects With Type 2 Diabetes Mellitus on a Background Medication of Metformin

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
700 (estimated)
Sponsor
Phenomix · Industry
Sex
All
Age
18 Years – 85 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to demonstrate the efficacy of dutogliptin over 26 weeks (as evidenced by placebo-corrected changes in HbA1c relative to baseline), to demonstrate safety and tolerability of dutogliptin, and to demonstrate changes in fasting plasma glucose over 26 weeks.

Conditions

Interventions

TypeNameDescription
DRUGdutogliptin400 mg
DRUGplacebo

Timeline

Start date
2009-05-01
Primary completion
2010-10-01
Completion
2010-12-01
First posted
2009-02-24
Last updated
2010-08-11

Locations

97 sites across 7 countries: United States, Argentina, Chile, Czechia, India, Peru, Poland

Source: ClinicalTrials.gov record NCT00850239. Inclusion in this directory is not an endorsement.