NCT00850200

Proton Therapy for Hodgkin Lymphoma

Improving the Therapeutic Ratio by Using Proton Beam Radiation Therapy for Patients With Stage IA-IIIBX (Bulky/Non-bulky) Hodgkin Lymphoma Involving the Mediastinum Following Standard Chemotherapy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (actual)
• Sponsor: University of Florida · Academic / Other
• Sex: All
• Age: 6 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to reduce the risk of radiation related side effects and complications by treating with radiation (protons or photons) that exposes less of normal organs to low dose radiation.

Detailed description

3 treatment plans will be created to deliver between a total of 21-39.6 Gray (Gy)/Centigray Equivalents (CGE) to the planning target volume (PTV). 1. Proton Plan 2. Conventional Plan 3. Intensity Modulated Radiotherapy (IMRT) Plan The patient will then receive the radiation modality with the lowest percentage of the body receiving 4 Gy (V4Gy/CGE)

Conditions

• Hodgkin Lymphoma

Interventions

Type	Name	Description
RADIATION	Proton Radiation Plan	Between 21-39.6 Gy/CGE to the PTV
RADIATION	Conventional Photon Radiation Plan	Between 21-39.6 Gy/CGE to the PTV
RADIATION	Intensity Modulated Radiation Plan	Between 21-39.6 Gy/CGE to the PTV

Timeline

• Start date: 2009-08-01
• Primary completion: 2013-05-01
• Completion: 2018-01-09
• First posted: 2009-02-24
• Last updated: 2019-01-31
• Results posted: 2014-03-21

Locations

1 site across 1 country: United States