NCT00846651

Spinal Anesthesia Induced Hypotension During Cesarean Section

Comparison of Phenylephrine Infusion With Colloids vs. Crystalloids for Reduction of Spinal-induced Hypotension During Cesarean Section

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 82 (actual)
• Sponsor: Milton S. Hershey Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 35 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to compare two methods for preventing low blood pressure associated with spinal anesthesia during Cesarean sections.

Detailed description

Many women experience low blood pressure after spinal anesthesia for Cesarean section. This low blood pressure may result in nausea, vomiting dizziness and impairment of uterine blood flow.The purpose of this study is to compare two methods for preventing low blood pressure associated with spinal anesthesia during Cesarean sections. In both methods, we will attempt to prevent low blood pressure using phenylephrine infusion that has been shown to be effective in recent research. In addition to receiving phenylephrine one group of patients will receive standard salt solution (Ringer's lactate solution), while the other group will receive a different, intravenous fluid called hydroxyethylstarch.

Conditions

• Hypotension

Interventions

Type	Name	Description
OTHER	Colloid administration	The patients received 0.5 L colloid solution (hydroxyethylstarch 6%) or 1.5 L Ringer lactate prior to spinal anesthesia for cesarean section.
OTHER	Crystalloid administration	The patients received 1.5 L Ringer lactate prior to spinal anesthesia for cesarean section.
DRUG	phenylephrine infusion	A phenylephrine infusion will be started immediately after performing the spinal anesthesia and continued until time of uterine incision.

Timeline

• Start date: 2009-02-01
• Primary completion: 2009-12-01
• Completion: 2010-02-01
• First posted: 2009-02-19
• Last updated: 2017-10-16
• Results posted: 2013-07-03

Locations

1 site across 1 country: United States