NCT00846599

Postprandial Endothelial Dysfunction After a High-Fat Meal in HIV-infected Men

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (estimated)
• Sponsor: Tufts University · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to examine the postprandial (anytime after a meal) effect of different dietary fats on endothelial function in HIV-infected and HIV-uninfected men.

Detailed description

This study requires two visits. Once determined eligible by the study criteria, during the first visit the participant will be randomly placed to receive one of two high-fat meals. The participant will receive the other study meal during the second visit. At each visit, brachial artery ultrasounds will be performed before and 3 hours after the meal is eaten. The sample size is 50 subjects. This study will be conducted at the Clinical Research Center at Tufts Medical Center.

Conditions

• HIV Infection
• Cardiovascular Risk
• HIV Infections

Interventions

Type	Name	Description
OTHER	Omega-3 study meal	Participant will eat a study meal high in omega-3 fatty acids.
OTHER	Saturated fat study meal	Participant will eat a study meal high in saturated fat.

Timeline

• Start date: 2008-01-01
• Primary completion: 2010-01-01
• Completion: 2010-01-01
• First posted: 2009-02-18
• Last updated: 2017-10-12

Locations

1 site across 1 country: United States