Clinical Trials Directory

Trials / Terminated

TerminatedNCT00839917

A Study of ProQuad™ in Healthy Children in Korea (V221-023)

A Multicenter, Randomized, Open-Label Study to Compare the Immunogenicity, Safety, and Tolerability of Measles, Mumps, Rubella, and Varicella of Combination Vaccine ProQuad With Concomitant Administration of M-M-R II and VARIVAX in Healthy Korean Children

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
30 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
All
Age
12 Months – 23 Months
Healthy volunteers
Accepted

Summary

This study will compare ProQuad™ and concomitant administration of M-M-R™ II and Varivax™ with respect to immunogenicity, safety and tolerability. The primary hypothesis to be tested is that the antibody response rates to measles, mumps, rubella, and varicella 6 weeks after vaccination with ProQuad™ will be non-inferior to the antibody response rates after vaccination with concomitant M-M-R™ II and Varivax™.

Conditions

Interventions

TypeNameDescription
BIOLOGICALMeasles, Mumps, Rubella and Varicella (Oka-Merck) Virus Vaccine Live (ProQuad™)Single administration of 0.5 mL subcutaneous injection
BIOLOGICALM-M-R™ II and Varivax™Single administration of 0.5 mL subcutaneous injection

Timeline

Start date
2008-02-01
Primary completion
2008-05-01
Completion
2008-05-01
First posted
2009-02-10
Last updated
2017-04-12
Results posted
2012-10-10

Source: ClinicalTrials.gov record NCT00839917. Inclusion in this directory is not an endorsement.

A Study of ProQuad™ in Healthy Children in Korea (V221-023) (NCT00839917) · Clinical Trials Directory