NCT00839085

Comparison of Ascorbic Acid and Grape Seed Extract in Oxidative Stress Induced by on Pump Heart Surgery

Effect of Ascorbic Acid and Grape Seed Extract "Vitis Vinifera L." in Oxidative Stress Induced by on Pump Coronary Artery by Pass Grafting Surgery

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 72 (actual)
• Sponsor: Tabriz University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Study aimed to compare the effect of grape seed extract and ascorbic acid in oxidative stress induced by on pump coronary artery by pass grafting surgery.

Detailed description

This study aimed to compare the effect of grape seed extract and ascorbic acid in oxidative stress induced by on pump coronary artery by pass grafting surgery. There are three groups in the study. 75 candidate of coronary artery by pass grafting surgery were assigned random allocation on the groups (25 in each group). 1. Control 2. GSE (100 mg/6h - PO, 24h before surgery) 3. Vit C (25 mg/kg in pump circulation during surgery)

Conditions

• CABG-Induced Oxidative Stress

Interventions

Type	Name	Description
DRUG	GSE	grape seed extract (100 mg/6h), PO
DRUG	Vit C (Ascorbic Acid)	Vit C 25 mg/ kg

Timeline

• Start date: 2008-11-01
• Primary completion: 2009-01-01
• Completion: 2009-03-01
• First posted: 2009-02-09
• Last updated: 2009-02-10

Locations

1 site across 1 country: Iran