NCT00837668

Stromal Gene Expression During Pulmonary Sarcoidosis

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 110 (estimated)
• Sponsor: Ohio State University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

to determine the genetic pathways operating at the tissue level to cause granulomatous inflammation in the lungs and lymph nodes of patients with sarcoidosis. By so doing, we hope to identify unique genetic mechanisms which will aid in the diagnosis of sarcoidosis and will help us understand the pathogenesis of this poorly understood disease.

Detailed description

to collect small sample of lung tissue recovered from a clinical procedure such as bronchoscopy, or a mediastinoscopy (a procedure in which a lighted instrument (mediastinoscope) is inserted through a neck incision to visually examine the structures in the top of the chest cavity and to take a sample (biopsy) of tissue.

Conditions

• Sarcoidosis

Timeline

• Start date: 2005-04-01
• Primary completion: 2012-02-01
• Completion: 2012-02-01
• First posted: 2009-02-05
• Last updated: 2017-06-14

Locations

1 site across 1 country: United States