NCT00834236

Proteiomic Fingerprints of Gastric Juice

Diagnosis of Gastroduodenal Diseases by Proteiomic Fingerprints of Gastric Juice

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 76 (actual)
• Sponsor: Kaohsiung Veterans General Hospital. · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

No accurate, inexpensive and non-invasive test for gastric cancer screening is currently available. The investigators' recent study identified a1-antitrypsin and other proteins as potential biomarkers of gastric cancer in gastric juice. The aim of this study was to develop a novel non-invasive modality for detecting gastric cancer by measurement of biomarkers in gastric juice.

Detailed description

Patients and methods: The study consisted of two parts: (1) investigating the differences in gastric juice biomarker concentrations between gastric cancer patients and controls, and (2) screening gastric cancer using string test to obtain gastric juice followed by immunoassay for biomarker concentration.

Conditions

• Gastric Cancer

Interventions

Type	Name	Description
OTHER	normal subject	biomarker in gastric juice, i.e., alpha 1-antitrypsin, CEA
OTHER	gastric cancer	biomarker in gastric juice, e.g., alpha 1-antitrypsin

Timeline

• Start date: 2008-03-01
• Primary completion: 2011-03-01
• Completion: 2011-03-01
• First posted: 2009-02-03
• Last updated: 2015-12-07
• Results posted: 2015-12-07

Locations

2 sites across 1 country: Taiwan