NCT00833092

Magnesium Nutrition and Sleep Behavior in Older Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 111 (actual)
• Sponsor: USDA Grand Forks Human Nutrition Research Center · Federal
• Sex: All
• Age: 51 Years
• Healthy volunteers: Accepted

Summary

Insomnia is not a natural part of aging but is higher in older adults because of a variety of factors common in later life. One of these factors may be a deficient magnesium status. This study will look at whether or not magnesium supplementation will improve sleep.

Detailed description

Insomnia affects approximately one-third of older Americans. More than half of all people aged 65 and older experience sleep problems. The prevalence of insomnia and other sleep disorders is not a natural part of aging but is high in older adults because of a variety of factors common in late life. One of those factors may be a deficient magnesium status. There is a close association between sleep architecture, especially slow wave sleep, and activity in the glutamatergic and gamma-aminobutyric acid (GABA) system. Because magnesium is a natural N-methyl-D-aspartate (NMDA)antagonist and GABA agonist, magnesium apparently plays a key role in the regulation of sleep. Such a role is supported by supplementation, correlation, and animal studies showing that magnesium intake or status affects sleep organization.

Conditions

• Nutritional Deficiency
• Insomnia

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Sugar Pill	Sugar pill supplementation for 9 weeks
DIETARY_SUPPLEMENT	magnesium	300 milligrams daily for 8 weeks

Timeline

• Start date: 2008-01-01
• Primary completion: 2008-12-01
• Completion: 2008-12-01
• First posted: 2009-01-30
• Last updated: 2015-03-26
• Results posted: 2012-04-04

Locations

1 site across 1 country: United States