Trials / Completed
CompletedNCT00832663
Influence of Non-steroidal Anti-inflammatory Drugs (NSAID) on Muscle Regeneration
The Influence of Blocking Inflammatory Activity in Vivo on Skeletal Muscle Regeneration in Humans
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 32 (actual)
- Sponsor
- Bispebjerg Hospital · Academic / Other
- Sex
- Male
- Age
- 18 Years – 35 Years
- Healthy volunteers
- Accepted
Summary
The purpose of this study is to determine the influence of non-steroidal anti-inflammatory drugs (NSAIDs) on muscle regeneration. The investigators' hypothesis is that ingestion of NSAID will delay or impair muscle regeneration.
Detailed description
The model employed to induce muscle damage is electrical stimulation. Muscle biopsies will be examined to follow the response of satellite cells and muscle regeneration. Study participants will be randomly assigned to a placebo or NSAID group in a double-blinded manner.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | NSAID | Effect of NSAID ingestion on muscle regeneration |
| DRUG | placebo | receive placebo |
Timeline
- Start date
- 2009-04-01
- Primary completion
- 2009-12-01
- Completion
- 2009-12-01
- First posted
- 2009-01-30
- Last updated
- 2010-03-16
Locations
1 site across 1 country: Denmark
Source: ClinicalTrials.gov record NCT00832663. Inclusion in this directory is not an endorsement.