Trials / Completed
CompletedNCT00831454
Identification of EGFR-TKIs Sensitivity or Resistance Markers in NSCLC May Help in Optimal Patient Selection
Relationship of Polymorphisms and Mutations of Epidermal Growth Factor Receptor and Tyrosine Kinase Inhibitors Responsiveness in Non-small-cell Lung Cancer Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 51 (actual)
- Sponsor
- Armando Santoro, MD · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The aim of this study was to retrospectively evaluate associations between EGFR and AKT DNA-polymorphisms involved in transcriptional regulation and overall survival in NSCLC patients treated with EGFR-TKIs.
Detailed description
DNA will be isolated from blood samples or paraffin-embedded tumor specimens and than a mutation analysis and SNPs genotyping will be done.
Conditions
Timeline
- Start date
- 2008-09-01
- Primary completion
- 2011-12-01
- Completion
- 2011-12-01
- First posted
- 2009-01-29
- Last updated
- 2014-12-02
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT00831454. Inclusion in this directory is not an endorsement.