NCT00830986

Cognition Following Computer Assisted Total Knee Arthroplasty

Cognition Following Computer Assisted Total Knee Arthroplasty: A Prospective Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 100 (actual)
• Sponsor: Rothman Institute Orthopaedics · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

A significant number of patients experience postoperative cognitive changes following total joint arthroplasty. Among other causes, the mental status change may be the result of fat and bone marrow debris embolization. We hypothesized that the use of computer assisted total knee arthroplasty, which does not utilize intramedullary alignment rods, would produce less fat and bone marrow debris embolization and, hence, fewer mental status changes.

Detailed description

Inclusion criteria * Primary, cemented knee arthroplasty * Unilateral or bilateral TKA Exclusion criteria * Patient is unable to speak English * Unable to read and write * Patient with history of psychiatric disorders (Depression, Schizophrenia, anxiety, bipolar dis.) * Patients with history of IV drug abuse * Previous history of dementia * Patients on mental status changing medications

Conditions

• Cognition
• Embolism, Fat

Interventions

Type	Name	Description
DEVICE	Total Knee Arthroplasty Implant (Scorpio®)	Implantation of a Total Knee Arthroplasty using Conventional Intramedullary Instrumentation
DEVICE	Total Knee Arthroplasty Implant (Scorpio®)	Implantation of a Total Knee Arthroplasty using a Computer Assisted Software, without Intramedullary Instrumentation

Timeline

• Start date: 2005-07-01
• Primary completion: 2006-03-01
• Completion: 2006-03-01
• First posted: 2009-01-28
• Last updated: 2009-04-16