NCT00830843

Inhalatorial Sedation in Patient With Subarachnoid Hemorrhage (SAH) Versus Conventional Intravenous Sedation

Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 13 (actual)
• Sponsor: Azienda Ospedaliera San Gerardo di Monza · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Recent study has shown that inhalatory sedation is a practicable, effective and not risky method in Intensive Care Unit. Sevoflurane effect on cerebral system have been described in previous studies: it causes an increasing of cerebral blood flow and a decrease of oxygen cerebral consumption. Clinical strategy for Subarachnoid Hemorrhage is orientated to increase cerebral blood flow to limit vasospasm phenomena after SAH. Scope of this study is to evaluate the Cerebral Blood Flow variation associated to Isoflurane sedation versus conventional sedation with propofol .

Conditions

• Stroke
• Subarachnoid Hemorrhage

Interventions

Type	Name	Description
DRUG	Propofol	Propofol(3-4 mg/kg/ora)administrated for 2 hours.
DRUG	Isoflurane	Isoflurane inhalatorial administration for 2 hours at 0.8-1.0% Minimum Alveolar Concentration

Timeline

• Start date: 2009-01-01
• Primary completion: 2011-07-01
• Completion: 2011-07-01
• First posted: 2009-01-28
• Last updated: 2016-08-22

Locations

1 site across 1 country: Italy