NCT00828399

Prevention of Acute Radiation Enteritis With Glutamine

Efficacy of Glutamine in the Prevention of Acute Radiation Enteritis Among Patients Treated With Radiation of Abdomen and Pelvis.

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 70 (actual)
• Sponsor: Castilla-León Health Service · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Ionizing radiation has cytotoxic effects, and is commonly used as treatment for neoplasm. A common adverse effect of radiation is acute diarrhoea. Glutamine is an aminoacid with antioxidant effects that can protect tissues of damage dued to radiation. The investigators designed a randomized, double-blind trial phase III to study if glutamine prevents acute radiation enteritis.

Conditions

• Acute Radiation Enteritis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Glutamine	Oral glutamine 30g/day
DIETARY_SUPPLEMENT	Whole protein	Oral whole protein 30 g/day

Timeline

• Start date: 2009-01-01
• Primary completion: 2011-05-01
• Completion: 2011-05-01
• First posted: 2009-01-23
• Last updated: 2011-05-25

Locations

1 site across 1 country: Spain