NCT00826631

How Does 4 Weeks of Increased Fast Food Intake Affect Metabolism?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 36 (actual)
• Sponsor: University Hospital, Linkoeping · Academic / Other
• Sex: All
• Age: 18 Years – 45 Years
• Healthy volunteers: Accepted

Summary

Objective: To study the effect of fast food-based hyper-alimentation on liver enzymes and hepatic triglyceride content (HTGC)and metabolism. Design: Prospective interventional study with parallel control group. Setting University Hospital of Linköping, Sweden. Participants: 12 healthy men and six healthy women with a mean (SD) age of 26 (6.6) years and a matched control group. Intervention: Subjects in the intervention group aimed for a body weight increase of 5-15% by eating at least two fast food-based meals a day with the goal to double the regular caloric intake in combination with adoption of a sedentary lifestyle for four weeks. Main outcome measures: Weekly changes of serum aminotransferases and HTGC measured by proton nuclear magnetic resonance-spectroscopy at baseline and after the intervention.

Conditions

• Hyper-Alimentation
• Healthy

Interventions

Type	Name	Description
PROCEDURE	Fast food arm	Doubling of regular caloric intake based on fast food, no exercise allowed

Timeline

• Start date: 2006-04-01
• Primary completion: 2007-12-01
• Completion: 2009-01-01
• First posted: 2009-01-22
• Last updated: 2009-01-22

Locations

1 site across 1 country: Sweden