Trials / Completed
CompletedNCT00824772
Evaluation of Pharmacogenetic Factors Affecting Fentanyl Requirements for Postoperative Pain Control
Evaluation of Pharmacogenetic Factors Contributing to Dose Requirement of Fentanyl for Postoperative Pain Control: Genetic Polymorphisms of OPRM1, ABCB1, CYP3A4 and CYP3A5
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 204 (actual)
- Sponsor
- Inje University · Academic / Other
- Sex
- Female
- Age
- 19 Years – 65 Years
- Healthy volunteers
- Not accepted
Summary
Fentanyl is a widely used opioid analgesic. There are big interindividual variabilities in dose requirements of fentanyl for postoperative pain control. This study aims to reveal the genetic factors affecting the variable requirements of fentanyl during postoperative period.
Detailed description
The candidate genes are OPRM1, ABCB1,CYP3A4 and CYP3A5.
Conditions
Timeline
- Start date
- 2008-09-01
- Primary completion
- 2010-12-01
- Completion
- 2012-12-01
- First posted
- 2009-01-19
- Last updated
- 2013-06-04
- Results posted
- 2013-05-27
Locations
1 site across 1 country: South Korea
Source: ClinicalTrials.gov record NCT00824772. Inclusion in this directory is not an endorsement.