NCT00822328

Fermented Milk Drink on Human Intestinal Microflora

Effects of a Fermented Milk Drink Containing Lactobacillus Casei Strain Shirota on the Human Intestinal Microflora

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Cheng Hsin Rehabilitation Medical Center · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Fermented milk is a popular drink. Recent studies revealed that some fermented milk containing some strains of lactic acid bacteria have health-promoting effects through improvement of the intestinal microflora and modulation of the immune system. Lactobacillus casei strain Shirota (LcS) is a probiotic bacterium used in the production of fermented milk products and lactic acid bacteria preparations. LcS has been shown to modify allergen-induced immune responses in allergic rhinitis, altering fermentation patterns in the small bowel, prevention of recurrent urinary tract infections in women. Yakult®300 is a fermented milk containing at least 3x10\^10 live LcS cells per 100 ml bottle. This study aimed to evaluate the effects of a fermented milk drink containing Lactobacillus casei strain Shirota on the human intestinal microflora.

Conditions

• Signs and Symptoms, Digestive

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Yakult®300	Yakult®300 was given 100 ml once per day for four weeks. Fermented or unfermented milk per 100 ml bottle per day for four week.
DIETARY_SUPPLEMENT	Lactobacillus casei strain Shirota	Lactobacillus casei strain Shirota

Timeline

• Start date: 2009-01-01
• Primary completion: 2009-03-01
• Completion: 2009-03-01
• First posted: 2009-01-14
• Last updated: 2009-09-02
• Results posted: 2009-08-19

Locations

1 site across 1 country: Taiwan