NCT00821899

Bone Marrow Autotransplantation in Type 1 Diabetes

Regeneration of Insulin Production in Patients With Type 1 Diabetes by Autologous Bone Marrow Blood Infusion

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: Hospital Clinic of Barcelona · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

This project evaluates the effectiveness of the administration of autologous bone marrow blood in patients with brittle type 1 diabetes mellitus to restore insulin secretion. After mobilization of hematopoietic progenitors (G-CSF) during 3 days, 50 to 90 mL of bone marrow blood will be obtained by multifunction in the posterior iliac crest. The material obtained will be implanted into the pancreas through the magna pancreatic artery after femoral catheterization.

Conditions

• Type 1 Diabetes Mellitus

Interventions

Type	Name	Description
BIOLOGICAL	administration of autologous bone marrow blood	administration of autologous bone marrow blood through magna pancreatic artery after femoral catheterization once during 12-month study period

Timeline

• Start date: 2009-01-01
• Primary completion: 2010-05-01
• Completion: 2010-05-01
• First posted: 2009-01-14
• Last updated: 2012-03-20

Locations

2 sites across 1 country: Spain