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CompletedNCT00820664

A Clinical Study to Evaluate the Effects of Estrogen in Healthy Postmenopausal Women

A Randomized Clinical Trial to Evaluate the Effects of Estrogen on Uterine Endometrium in Healthy Postmenopausal Women

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
29 (actual)
Sponsor
Merck Sharp & Dohme LLC · Industry
Sex
Female
Age
18 Years – 65 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to examine the effect of two different dose levels of estrogen or placebo in healthy postmenopausal women by measuring the changes in hormone levels and examining the changes in the uterine lining (endometrium).

Conditions

Interventions

TypeNameDescription
DRUGComparator: Estrace 0.5 mg0.5 mg tablet taken once daily for 28 days
DRUGComparator: Estrace 2 mg2 mg tablets taken once daily for 28 days.
DRUGComparator: PlaceboPlacebo 0 mg capsule taken once daily for 28 days

Timeline

Start date
2008-12-01
Primary completion
2009-05-01
Completion
2009-05-01
First posted
2009-01-12
Last updated
2016-01-22
Results posted
2010-05-07

Source: ClinicalTrials.gov record NCT00820664. Inclusion in this directory is not an endorsement.

A Clinical Study to Evaluate the Effects of Estrogen in Healthy Postmenopausal Women (NCT00820664) · Clinical Trials Directory