NCT00820534

A Comparative Study of the Efficacy of Penciclovir 10mg/g (1%) Cream in Preventing the Appearance of Classical Lesion in Recurrent Cold Sore Sufferers

A Randomised, Double-blind, Vehicle Controlled, Single Center, Parallel Group, Comparative Study of the Efficacy of Penciclovir 10mg/g (1%) Cream in Preventing the Appearance of Classical Lesion in Recurrent Cold Sore Sufferers

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 126 (actual)
• Sponsor: Novartis · Industry
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Comparison of the efficacy of penciclovir 10 mg/g (1%) cream with that of vehicle at 72 hours in preventing the appearance of classical lesions following prodromal symptoms (tingling or burning sensation) based on thermographic assessment among recurrent cold sore sufferers.

Conditions

• Cold Sore

Interventions

Type	Name	Description
DRUG	Penciclovir	Penciclovir every 2 hours during waking hours for 96 hours
DRUG	Placebo	Placebo every 2 hous during waking hours for 96 hours

Timeline

• Start date: 2008-12-01
• Primary completion: 2009-11-01
• Completion: 2009-11-01
• First posted: 2009-01-12
• Last updated: 2012-04-20
• Results posted: 2011-01-19

Locations

1 site across 1 country: United Kingdom