NCT00810524

Influence of Antiviral Treatment to the Long-Term Prognosis of Patients With Chronic HBV Infection

Influence of Antiviral Treatment to the Long-Term Prognosis of Patients With Chronic HBV Infection.

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 600 (estimated)
• Sponsor: Sun Yat-sen University · Academic / Other
• Sex: All
• Age: 20 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Influence of antiviral treatment to the long term prognosis of patients with chronic HBV infection. The aim of antiviral treatment for HBV is to reduce the long term severe complications. In this study, the investigators divided patients with chronic HBV infection into two groups, which start early antiviral treatment and conventional antiviral treatment respectively. All the patients will be followed for ten years. From this study, the investigators want to find out the optimal time for patients with chronic HBV infection to start antiviral treatment.

Conditions

• Hepatitis B, Chronic

Interventions

Type	Name	Description
DRUG	lamivudine	100mg, P.O.,QD, duration: until HBeAg seroconversion for more than 2years.
DRUG	Telbivudine	600mg, P.O.,QD, duration: until HBeAg seroconversion for more than 2years.
DRUG	Enticavir	0.5mg, P.O.,QD, duration: until HBeAg seroconversion for more than 2 years.
DRUG	Adefovir Dipivoxil Tablets	10mg, P.O.,QD, duration: until HBeAg seroconversion for more than 2years.

Timeline

• Start date: 2007-01-01
• Primary completion: 2017-01-01
• Completion: 2017-01-01
• First posted: 2008-12-18
• Last updated: 2008-12-18

Locations

2 sites across 1 country: China