NCT00805714

Livalo Acute Myocardial Infarction Study

A Prospective Clinical Observation Study to Evaluate the Influence of Long Term Treatment of Pitavastatin on the Therapeutic Prognosis and Safety in Acute Myocardial Infarction

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,128 (actual)
• Sponsor: JW Pharmaceutical · Industry
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Statins are usually used in AMI patients due to its strong anti-lipidemic effect, pleiotropic effect and tolerable safety profiles. Generally AMI patients are prescribed many drugs concomitantly; there are some risks due to the drug interaction. Especially, statins are reported to have many drug interactions, these might influence to therapeutic prognosis and safety in AMI patients. This study is conducted to administer the non-CYP3A4 metabolized statin, pitavastatin to AMI patients over 1 year, and the results will be compared with the other results from the KAMIR study which is expected to the large scale of AMI patients using statins be enrolled. Finally, from that comparison, we will investigate the influence of the statins metabolism by CYP3A4 to the therapeutic prognosis like death, major adverse cardiac events(MACE), and major ADR of statins like CK increase, myalgia.

Conditions

• Acute Myocardial Infarction

Timeline

• Start date: 2007-04-01
• Primary completion: 2010-08-01
• Completion: 2011-03-01
• First posted: 2008-12-10
• Last updated: 2012-03-30

Locations

10 sites across 1 country: South Korea