NCT00805506

Evaluation of Glucose Monitoring Methods: Characterizing Glycemic Control in Subjects With Diabetes

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 16 (actual)
• Sponsor: HealthPartners Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Evaluate the usefulness of continuous glucose monitoring devices in terms of their ability to identify periods throughout the day when glucose varies significantly.

Detailed description

Many CGM systems use a surrogate for blood glucose--tissue glucose or interstitial glucose. Interstitial fluid (ISF) is the medium for these approaches. A physiological lag in ISF glucose relative to capillary blood glucose has been noted, probably due to relatively low blood perfusion at the sampling site. 9 This physiological lag can result in an accuracy error, manifesting as a significant bias between blood and tissue glucose, particularly during periods of rapid glucose change. This lag error might be particularly meaningful when glucose is rapidly dropping towards hypoglycemia.

Conditions

• Diabetes

Timeline

• Start date: 2006-02-01
• Primary completion: 2007-04-01
• Completion: 2007-04-01
• First posted: 2008-12-09
• Last updated: 2015-11-26

Locations

1 site across 1 country: United States