Trials / Completed
CompletedNCT00804219
Humoral and Cellular Immunity of Low and High-responders After Tick-borne Encephalitis Vaccination
Characterization of Humoral and Cellular Immunity of Low and High-responders After TBE Vaccination
- Status
- Completed
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 67 (actual)
- Sponsor
- Medical University of Vienna · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Accepted
Summary
The phenomenon of no- and low-responsiveness has been described after applications of different vaccines (e.g. hepatitis B, TBE) and is concerning about 2-10% of the vaccinees. The aim of this project is to investigate the humoral and cellular immune responses of low-responders after TBE vaccination in order to find parameters regarding immunoregulation against TBE. It is of interest if non-responsiveness is a general immunological deficit of a distinct patient group or if it is a antigen-specific phenomenon.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | TBE vaccination and influenza vaccination | FSME-Immun, 0,5 ml, i.m., 1x Inflexal 0,5 ml, i.m., 1x |
Timeline
- Start date
- 2008-12-01
- Primary completion
- 2010-11-01
- Completion
- 2010-11-01
- First posted
- 2008-12-08
- Last updated
- 2011-07-22
Locations
1 site across 1 country: Austria
Source: ClinicalTrials.gov record NCT00804219. Inclusion in this directory is not an endorsement.