NCT00803803

Dose, Effects and Characteristics of Pilocarpine

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 37 (actual)
• Sponsor: Wills Eye · Academic / Other
• Sex: All
• Age: 18 Years – 90 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this investigation, in which pilocarpine was given in repeated doses, was to evaluate: Part I - the effects of different concentrations of pilocarpine hydrochloride on intraocular pressure. Part II -the effects on intraocular pressure of glaucomatous patients to pilocarpine 2% when given once, twice and four daily. In addition, we studied various attributes of the eye which may serve as indicators of responsiveness of individual patients to pilocarpine.

Detailed description

In addition, we studied various attributes of the eye which may serve as indicators of responsiveness of individual patients to pilocarpine.

Conditions

• Open-angle Glaucoma

Interventions

Type	Name	Description
DRUG	Pilocarpine Concentration	Varying concentration 0.5 to 8%
DRUG	Pilocarpine Frequency	1 to 4 times daily

Timeline

• Start date: 1978-08-01
• Primary completion: 1979-08-01
• Completion: 1979-12-01
• First posted: 2008-12-08
• Last updated: 2016-11-22

Locations

1 site across 1 country: United States