NCT00803699

Predicting Dietary Selenium Needs to Achieve Target Blood Selenium Levels

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 262 (actual)
• Sponsor: USDA Grand Forks Human Nutrition Research Center · Federal
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

In this study, we will evaluate the effectiveness of several doses of oral selenomethionine in raising biomarkers of selenium status including plasma selenium concentrations.

Detailed description

Results of studies with animal tumor models and human clinical trials suggest that the essential nutrient selenium can be anti-tumorigenic if consumed at levels greater than nutritional requirements. If it is possible to increase plasma selenium concentrations above 120 nanograms per milliliter with less than 200 micrograms of selenium daily, then it is possible that supplementation can be accomplished through the use of selenium-containing foods.

Conditions

• Nutritional Requirements

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	placebo	daily placebo capsules for 12 months
DIETARY_SUPPLEMENT	selenium as L-selenomethionine	daily capsules of 50, 100, or 200 micrograms of L-selenomethionine for 12 months

Timeline

• Start date: 2005-11-01
• Primary completion: 2007-09-01
• Completion: 2007-09-01
• First posted: 2008-12-05
• Last updated: 2018-05-29

Locations

1 site across 1 country: United States