Trials / Completed
CompletedNCT00798278
Urokinase Versus Video-assisted Thoracoscopic to Treat Complicated Parapneumonic Empyema in Childhood
Exploratory Multicentre Clinical Trial to Compare the Efficacy of Urokinase Versus Video-assisted Thoracoscopic for Treatment of Complicated Parapneumonic Empyema in Childhood
- Status
- Completed
- Phase
- Phase 3
- Study type
- Interventional
- Enrollment
- 200 (estimated)
- Sponsor
- Spanish Society of Pediatric Surgery · Academic / Other
- Sex
- All
- Age
- 1 Year – 15 Years
- Healthy volunteers
- Not accepted
Summary
A great controversy exists about which is the best method to perform the evacuation of the collection. The purpose of this study is to evaluate which is the best initial treatment to drain complicated parapneumonic empyema (stages II and III) in children: the present study raises a hypothesis of equivalence between both arms of treatment (chest drainage plus intrapleural urokinase or videothoracoscopic debridement).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Urokinase | Chest tube with intrapleural urokinase infusion for 3 days |
| PROCEDURE | Video-Assisted Thoracoscopic | Video-Assisted Thoracoscopic decortication |
Timeline
- Start date
- 2008-07-01
- Primary completion
- 2010-09-01
- Completion
- 2010-09-01
- First posted
- 2008-11-26
- Last updated
- 2010-10-28
Locations
6 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT00798278. Inclusion in this directory is not an endorsement.