NCT00798226

Fish Oil Supplementation During Pregnancy for Prevention of Asthma, Eczema and Allergies in Childhood

Fish Oil Supplementation During Pregnancy for Prevention of Asthma, Eczema and Allergies in Childhood: Interventional Trial in the COPSAC2010 (Copenhagen Studies on Asthma in Childhood) Birth Cohort

• Status: Active Not Recruiting
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 800 (estimated)
• Sponsor: Copenhagen Studies on Asthma in Childhood · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to prevent asthma and allergies in childhood by supplementation with fish oil (n-3 fatty acids) to the mother during pregnancy. Paticipants are mother and children participating in the ABC-(Asthma Begins in Childhood)cohort. Mothers are recruited during pregnancy and receive supplement with n-3 fatty acids or olive oil (placebo) from week 24 of gestation to 1 week after delivery. The child is followed with acute and planned visit at the research unit and diagnosis of disease is done in the research unit according to predefined algorithms.

Conditions

• Asthma
• Eczema
• Allergy

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	n-3 fatty acid	Oral intake of 4 capsules daily from week 24 of gestation to 1 week after delivery
DIETARY_SUPPLEMENT	olive oil	Oral intake of 4 capsules (1 g) daily from 24 weeks of gestation to 1 week after delivery

Timeline

• Start date: 2008-11-26
• Primary completion: 2027-07-01
• Completion: 2027-07-01
• First posted: 2008-11-26
• Last updated: 2025-04-13

Locations

2 sites across 1 country: Denmark