NCT00797264

Ketamine Associated With Morphine PCA After Total Hip Arthroplasty

Impact of the Route of Administration of Ketamine Associated With Morphine PCA on Analgesia After Total Hip Arthroplasty

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: Assistance Publique - Hôpitaux de Paris · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Ketamine (an analgesic drug often associated with morphine in the treatment of Opioid Induced Hyperalgesia) is often mixed in Morphine PCA syringe. We make the hypothesis that ketamine administrated separately via a continuous infusion, could induced a better analgesic effect. We will perform a randomised double blind study to determine the best infusion mode of intravenous ketamine, associated with morphine in PCA syringe or alone in continuous infusion.

Detailed description

Double blind study to determine the best infusion mode of intravenous ketamine, associated with morphine in PCA syringe or alone in continuous infusion

Conditions

• Arthroplasty, Replacement, Hip

Interventions

Type	Name	Description
DRUG	Ketamine-Morphine	Ketamine bolus preoperative and syringe pump peroperative, and morphine postoperative (PCA)
DRUG	Morphine	Bolus preoperative of NaCl and syringe pump peroperative of NaCl, and morphine postoperative (PCA)
DRUG	Postoperative PCA of Ketamine and morphine	Bolus preoperative of NaCl and syringe pump peroperative of Ketamine, and morphine postoperative (PCA)

Timeline

• Start date: 2008-11-01
• Primary completion: 2010-10-01
• Completion: 2010-10-01
• First posted: 2008-11-25
• Last updated: 2013-04-11

Locations

1 site across 1 country: France