Trials / Completed
CompletedNCT00795249
Effects of Chronic Smoking on Circulating Endothelial and Platelet-derived Microparticle
- Status
- Completed
- Phase
- EARLY_Phase 1
- Study type
- Interventional
- Enrollment
- 100 (actual)
- Sponsor
- Kurume University · Academic / Other
- Sex
- Male
- Age
- 20 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
The investigators hypothesized that circulating EMP is a useful surrogate marker of early stage of endothelial damage. To determine the effects of chronic smoking on circulating EMP, from healthy volunteers who have habit of chronic smoking, peripheral blood is drawn at the time of flow-mediated dilatation (FMD) examination. Spot urine is also collected. Circulating EMPs are counted using flow-cytometry. After 2-week smoking cessation, the measurements were repeated.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | smoking cessation | After baseline examination, the group is asked to quit smoking for 2 weeks. |
Timeline
- Start date
- 2008-11-01
- Primary completion
- 2010-11-01
- Completion
- 2010-11-01
- First posted
- 2008-11-21
- Last updated
- 2011-06-23
Locations
1 site across 1 country: Japan
Source: ClinicalTrials.gov record NCT00795249. Inclusion in this directory is not an endorsement.